Part 182 -- Substances Generally Recognized As Safe. Tsi, D. and Tan, A. View abstract. J Pharm Biomed Anal 2007;44(2):450-455. 2017;32:41-48. Kiso, Y. Antioxidative roles of sesamin, a functional lignan in sesame seed, and it's effect on lipid- and alcohol-metabolism in the liver: a DNA microarray study. Exp Biol Med (Maywood) 2007;232(6):754-761. Anagnostis, A. and Papadopoulos, A. I. Leduc, V., Moneret-Vautrin, D. A., Tzen, J. T., Morisset, M., Guerin, L., and Kanny, G. Identification of oleosins as major allergens in sesame seed allergic patients. Kiran, K. and Asad, M. Wound healing activity of Sesamum indicum L seed and oil in rats. A. Sesamin has not been found to cause any negative side effects in most healthy adults. View abstract. Therefore, development of new therapeutic strategies is needed as alternative or supplement to current asthma treatments. 2019;47:102183. Sesamin, as sold commercially and as used in the great majority of the literature, is actually a 50-50 mixture of sesamin and its isomer epi-sesamin. Phan, T. G., Strasser, S. I., Koorey, D., McCaughan, G. W., Rimmer, J., Dunckley, H., Goddard, L., and Adelstein, S. Passive transfer of nut allergy after liver transplantation. J Nutr 1993;123(11):1852-1858. The ability of this stuff to trim fat off was just as good if not better than the well proven and now banned triple stack of aspirin/caffeine/ephedra but Sesamin has none of the side effects! Wankhede, D. B. and Tharanathan, R. N. Sesame (Sesamum indicum) carbohydrates. [Flavones from flowers of Sesamum indicum]. View abstract. Shimizu, S., Akimoto, K., Shinmen, Y., Kawashima, H., Sugano, M., and Yamada, H. Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acid biosynthesis. Fewer problems with dry nasal mucous membranes following local use of sesame oil. Bhaskaran, S., Santanam, N., Penumetcha, M., and Parthasarathy, S. Inhibition of atherosclerosis in low-density lipoprotein receptor-negative mice by sesame oil. Prostaglandins Leukot Essent Fatty Acids 1998;58(3):185-191. The effects of ground sesame seeds (Ardeh) and sunflower oil on the serum lipid profile of the rats [Farsi]. J Am Acad Dermatol 2000;42(2 Pt 1):292-294. Diet is the primary source of human exposure to phytoestrogens. A., Andersson, R. E., and Kamal-Eldin, A. Neuroreport 2003;14(14):1815-1819. Sesamin has effect … Nutr Metab Cardiovasc Dis 2009;19(11):774-780. View abstract. View abstract. J Agric Food Chem 2007;55(21):8717-8722. Hsu, D. Z., Chen, K. T., Chien, S. P., Li, Y. H., Huang, B. M., Chuang, Y. C., and Liu, M. Y. Sesame oil attenuates acute iron-induced lipid peroxidation-associated hepatic damage in mice. Contact Dermatitis 1987;17(3):133-135. View abstract. View abstract. Ann N Y Acad Sci 2005;1042:279-285. View abstract. J Nutr Sci Vitaminol (Tokyo) 2007;53(5):383-392. Effects of topical sesame oil on oxidative stress in rats. Always consult your physician prior to using any dietary supplements. Srinivasan, K. N. and Pugalendi, K. V. Effect of excessive intake of thermally oxidized sesame oil on lipids, lipid peroxidation and antioxidants' status in rats. Moazzami, A. View abstract. View abstract. Chiang, J. P., Hsu, D. Z., Tsai, J. C., Sheu, H. M., and Liu, M. Y. This article reviews what leptin is, how it works and if supplements can help you lose weight. Talpur, N., Echard, B., Dadgar, A., Aggarwal, S., Zhuang, C., Bagchi, D., and Preuss, H. G. Effects of Maitake mushroom fractions on blood pressure of Zucker fatty rats. View abstract. View abstract. View abstract. View abstract. Lawrence, J. F., Chadha, R. K., Iverson, F., McGuire, P., and Conacher, H. B. Brominated fatty acid distribution in tissues and fluids of rats fed brominated vegetable oils. Digestion 1980;20(1):36-49. Nakano, D., Itoh, C., Takaoka, M., Kiso, Y., Tanaka, T., and Matsumura, Y. Antihypertensive effect of sesamin. Using GABA for sleep improvement is a relatively new trend, but a promising one at that. Effects of sesamin on aortic oxidative stress and endothelial dysfunction in deoxycorticosterone acetate-salt hypertensive rats. Okura, T., Ibe, M., Umegaki, K., Shinozuka, K., and Yamada, S. Effects of dietary ingredients on function and expression of P-glycoprotein in human intestinal epithelial cells. View abstract. Arch Latinoam Nutr 1992;42(2):90-93. Sesamin is catered to be a nutritional supplement that confers antioxidant and antiinflammatory effects (if touting its health properties) or possibly being an estrogen receptor modulator and fat burner (if targeting atheltes or persons wishing to lose weight). Grougnet, R., Magiatis, P., Mitaku, S., Terzis, A., Tillequin, F., and Skaltsounis, A. L. New lignans from the perisperm of Sesamum indicum. Jeng, K. C., Hou, R. C., Wang, J. C., and Ping, L. I. Sesamin inhibits lipopolysaccharide-induced cytokine production by suppression of p38 mitogen-activated protein kinase and nuclear factor-kappaB. View abstract. View abstract. Arch Int Pharmacodyn Ther 1988;292:182-188. Available at: https://ecfr.gpoaccess.gov/cgi/t/text/text-idx?c=ecfr&sid= 786bafc6f6343634fbf79fcdca7061e1&rgn=div5&view= text&node=21:3.0.1.1.13&idno=21. 2019;33(9):2421-8. Sesamin, as sold commercially and as used in the great majority of the literature, is actually a 50-50 mixture of sesamin and its isomer epi-sesamin. View abstract. Int Arch Allergy Immunol 2006;140(3):270-276. Chen, P. R., Tsai, C. E., Chang, H., Liu, T. L., and Lee, C. C. Sesamol induces nitric oxide release from human umbilical vein endothelial cells. Phytother Res 2000;14:592-5. View abstract. A. Sesame oil in injectable gold: two drugs in one? Potential Side Effects of Sesame Extract Sesamin. Metabolism 1999;48(10):1303-1313. Sesame oil has a variety of culinary, medicinal, and cosmetic uses, with some even referring to it as the "queen of oilseeds." J Agric Food Chem 2006;54(17):6266-6270. J Agric Food Chem 2006;54(25):9544-9550. Therefore, development of new therapeutic strategies is needed as alternative or supplement to current asthma treatments. Biosci Biotechnol Biochem 2008;72(6):1626-1627. View abstract. When applied to the skin: Sesame is POSSIBLY SAFE when applied to the skin. J Allergy Clin Immunol 2002;110(1):154-159. Jan, K. C., Hwang, L. S., and Ho, C. T. Biotransformation of sesaminol triglucoside to mammalian lignans by intestinal microbiota. Overview of the ingredients contained. Lipids 2002;37(4):435-438. Brands; Health Foods : Sesamin EX; Brands Health Foods Sesamin EX. View abstract. Mosayebi, G., Ghazavi, A., Salehi, H., Payani, M. A., and Khazae, M. R. Effect of sesame oil on the inhibition of experimental autoimmune encephalomyelitis in C57BL/6 mice. It is marketed as a non-thermogenic fat loss aid with additional antioxidant properties, as well as having a beneficial effect on cholesterol levels. Menu. View abstract. Indian J Exp Biol 1999;37(1):50-55. Hou, R. C., Chen, H. L., Tzen, J. T., and Jeng, K. C. Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cells. Mol Cell Biochem 1999;195(1-2):143-153. View abstract. The control group showed an almost three-fold increase in cholesterol levels… View abstract. J Nutr 1999;129(10):1885-1890. Protection against development and maintenance of hypertension in stroke-prone spontaneously hypertensive rats. Environ Mol Mutagen 2005;45(1):90-95. Warren CM, Chadha AS, Sicherer SH. Matsumura, Y., Kita, S., Morimoto, S., Akimoto, K., Furuya, M., Oka, N., and Tanaka, T. Antihypertensive effect of sesamin. Lipids 1997;32(6):605-610. Anticancer Res 1992;12(4):1259-1265. View abstract. View abstract. Hu, Y. M., Wang, H., Ye, W. C., and Zhao, S. X. Takeuchi, H., Mooi, L. 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