Antiperistaltic agents are metabolized by the liver (diphenoxylate to an active form) and primarily excreted in the feces. Applies to loperamide: oral capsule, oral capsule liquid filled, oral liquid, oral solution, oral suspension, oral tablet, oral tablet chewableAlong with its needed effects, loperamide (the active ingredient contained in Imodium) may cause some unwanted effects. Cases of Torsades de Pointes, cardiac arrest, and death have been reported with the use of a higher than recommended dosages of loperamide hydrochloride. However, it should be used carefully. Brown JW "Toxic megacolon associated with loperamide therapy." Find patient medical information for Imodium Multi-Symptom Relief oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. In some cases, they may want to monitor your liver enzymes, he says. Imodium , an anti-diarrheal agent is mainly metabolized via two separate liver enzymes in our body: CYP3A4; CYP2C8; Zantac , an H2-antagonist used to reduce stomach acid, is a mild inhibitor of the CYP3A4 enzyme. There is a growing body of evidence that suggests that vitamin deficiencies can have adverse effects on the liver and cause elevated liver enzymes 1 7. Imodium … Upper right quadrant abdominal pain and tenderness 5. "Product Information. HONcode standard for trustworthy health information. It is also abused by people dependent on opioids to treat opioid withdrawal symptoms. Loperamide works by slowing the speed that material passes through th… 33 drugs cause high liver enzymes and liver pain April 28, 2016 What drugs cause abnormal high liver enzymes count in blood test results, get to know them may help you and your children heal faster and live healthier, many medications can be responsible for mild to moderate increase in the liver enzyme … Find everything you need to know about Loperamide (Imodium), including what it is used for, warnings, reviews, side effects, and interactions. If you take other drugs, talk to your doctor before taking Imodium A-D or Pepto-Bismol. Symptoms of mild to moderate elevation of liver enzymes may vary from no symptoms to the following: 1. A study published in the journal Current Opinion in Clinical Nutrition and Metabolic Care in May 2013 found that a choline deficiency can result in fatty liver, liver fibrosis and … This product also contains Ox Bile which is needed to replace the bile that can … "Product Information. Summary: Liver function test abnormal is found among people who take Imodium, especially for people who are female, 60+ old, have been taking the drug for < 1 month. Imodium (loperamide hydrochloride) is an antidiarrheal used to treat diarrhea. You currently have javascript disabled. Imodium is a safe medication for most people. Although genetics can’t be overlooked, this usually isn’t the cause of elevated liver enzymes … Learn more about Loperamide (Imodium… The blood test checks for raised levels of AST and ALT, which are enzymes that the liver releases when it becomes inflamed or damaged. Imodium capsules, syrup and instants all contain the active ingredient loperamide. An initial step in detecting liver damage is a simple blood test to determine the level of certain liver enzymes … These two medications do not get rid of the cause of the diarrhea, they only help control the symptoms. Teva Pharmaceuticals USA, North Wales, PA. 2. Some side effects may not be reported. Hepatic coma can … Taking steps to lower ALT levels through diet, exercise, and other methods can help the liver recover. High doses of loperamide can cause … We use data about you for a number of purposes explained in the links below. Ann Pharmacother 27 (1993): 369-70, 7. Oxycontin is a powerful pain reliever that works by having a … On a positive note I believe, these enzyme levels were only in the 100's and not in the 1000's. Check with your doctor immediately if any of the following side effects occur while taking loperamide: Some side effects of loperamide may occur that usually do not need medical attention. If you take other drugs, talk to your doctor before taking Imodium A-D or Pepto-Bismol. The FDA is alerting the public, health care providers, lab personnel, and lab test developers that biotin can significantly interfere with certain lab tests and cause … I take half an imodium every day to help control my IBS-D. Healthy elevations in bilirubin have also been known to b… Imodium works for me but iam alway worried of taking it because it can cause liver problems when taking it all the time i have read the back of the box and it says do not take it you have liver problems and how many of us dont know if we really might have liver problems because liver problems can cause the same symptoms of ibs i have had my liver … This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. You may report them to the FDA. The majority of Imodium A-D side effects result from incorrect dosage.Therefore, reducing Imodium dose can help eliminate most short-term adverse symptoms. Vitamin Deficiencies and Liver Enzymes. Simethicone belongs to the class of medications called antiflatulant (anti-gas) agents. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. A blood test can show elevated liver enzymes. Mental changes 6. Therapy with antiperistaltic agents should be administered with extreme caution in patients with hepatorenal disease or abnormal liver enzymes. Your doctor determines the cause by reviewing your medications, your signs and symptoms and, in some cases, other tests and procedures. J Clin Psychiatry 53 (1992): 450. Long-term side effects can … Liver blood tests are some of the most commonly performed blood tests. Alanine Transaminase (ALT): In most types of liver disease, the ALT level is higher than AST and the AST/ALT rati… The most common adverse events were constipation, flatulence, headache, nausea, and dizziness. Hill MA, Greason FC "Loperamide dependence." Jensen was not involved with the work. Some of the dosage forms listed on this page may not apply to the brand name Imodium. Imodium, the brand name for loperamide, is an over-the-counter drug for diarrhea. We study 5,740 people who take Loperamide hydrochloride or have Elevated liver enzymes. Imodium (loperamide) In this factsheet: How does Imodium work? This is because their side effects are the same. Family history of liver disease. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to loperamide: compounding powder, oral capsule, oral liquid, oral suspension, oral tablet, oral tablet chewable. Understanding the function of the liver, its role in recovering and responding to exercise, and how this affects critical biomarkers in a blood test will help you better interpret your results and draw an accurate conclusion. Although not all of these side effects may occur, if they do occur they may need medical attention. Oxycontin. How to stop diarrhea - any medicine or remedy suggestions? Fever 3. Other brands: Imotil, Diamode, Kao-Paverin, ciprofloxacin, Bactrim, sulfamethoxazole / trimethoprim, loperamide, Lomotil, neomycin, atropine / diphenoxylate, Florastor, Pepto-Bismol, bismuth subsalicylate. They can … Common (1% to 10%): Constipation, nausea, flatulence, dry mouth, abdominal cramp, colic, vomiting, meteorism, abdominal pain, Uncommon (0.1% to 1%): Abdominal discomfort, abdominal pain upper, dyspepsia, Rare (less than 0.1%): Ileus (including paralytic ileus), megacolon (including toxic megacolon), abdominal distension[Ref], Rare (less than 0.1%): Loss of consciousness, stupor, depressed level of consciousness, hypertonia, coordination abnormality, Postmarketing reports: Death, tiredness[Ref], Rare (less than 0.1%): Hypersensitivity reaction, anaphylactic reaction (including anaphylactic shock), anaphylactoid reaction[Ref], Postmarketing reports: QT/QTc prolongation, Torsades de Pointes, other ventricular arrhythmias, cardiac arrest[Ref], Rare (less than 0.1%): Bullous eruption (including Stevens-Johnson syndrome, toxic epidermal necrolysis, and erythema multiforme), angioedema, urticaria, pruritus[Ref], Rare (less than 0.1%): Urinary retention[Ref].